Due to it's high accuracy, RT-PCR is currently the CDC gold standard for determining an active viral infection of SARS-CoV-2. Saliva testing may be even more sensitive at detecting SARS-CoV-2 than nasopharyngeal swabs according to some studies.
Key points from studies on saliva testing:
- SARS-CoV-2 was detected in persons that are asymptomatic1
- Saliva was more accurate at detecting SARS-CoV-2 after the onset of infection
- Saliva was more accurate at detecting SARS-CoV-2 in asymptomatic health care workers
- In the same study, of the 13 asymptomatic health care workers who tested positive via saliva and were confirmed positive via additional testing at a CLIA lab, 7 nasopharyngeal samples tested negative
- A sample control measurement showed higher variation in sample quality in nasopharyngeal when compared with saliva, which may be an explanation for false negative results using nasopharyngeal sampling2
The W4H saliva PCR test is 99.99% accurate and is FDA authorized.